I recently decided to un-install Oblivion and delete all my mods and start right over. I wanna know if anybody can give me a list of mods that they use that they find essential. You can suggest as many as you like. If they're difficult to use, please explain how. :3

If I had to start over from scratch (which I did a little while back), the first mods I must have are all just for looks:

Female EyeCandy - Body Replacer (Underwear)
http://www.tessource.net/files/file.php?id=10168

Female EyeCandy - Body Replacer (Nude)
http://www.tessource.net/files/file.php?id=10171

Rens Beauty Pack
http://www.tesnexus.com/downloads/file.php?id=4431

Younger Hotter NPCs
http://www.tesnexus.com/downloads/file.php?id=5288

Apachii Goddess Store
http://www.tesnexus.com/downloads/file.php?id=13437

Lera and Pizz Hiyoko Store I can not recommend this one enough, I absolutely LOVE this mod.
http://www.tesnexus.com/downloads/file.php?id=15617

Needless to say, most of those are for female characters, my male character is still at the sewer exit. The Hiyoko Store does contain a large selection of male and gender nonspecific clothing.

Good start, thanks! What about some custom races, content, etc.?

Before you get 70 links to mystic elves, here's a little variety.

Cute Elves race
http://www.tesnexus.com/downloads/file.php?id=16120

Ainmhi Race
http://www.tesnexus.com/downloads/file.php?id=4926

Tabaxi Cat Race
http://www.tesnexus.com/downloads/file.php?id=9870

That last one comes in several different versions, I assume they are different species of cats.

Ren's Beauty includes Mystic Elves, doesn't it?

Yup.

Alright! Moar!

Any good gameplay mods? I have a few in mind but I wanna hear suggestions.

well Talkie Toaster's Companion Share and Recruit. one of my favrits actually. bothe versions are compatible with eachother i checked in OBMM and bothe of them have there strengths and weaknesses to offer. there's the Grand Vampire Expirence which really takes an asawm spin with Vampires

I'm not much for companions or vampires. Thanks for the suggestion though. Anything else? I for sure am getting OOO and MOE

oh MOE is a wonder if youw ant bugfixes try UOP

I was going to get that one too. What about weapon and content mods? Anything that changes the actual gameplay or interfaces?